- Product Name:
Human Adiponectin protein
- Product Abbreviation:
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
>90% by SDS-PAGE
Liquid, dissolved in 20mM Tris-HCl, 500mM NaCl, pH 8.0,10%glycerol
Aliquot and store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles
Calibrator or standard in ELISA and other possible application